Fixed-dose combinations of antiretrovirals are multiple antiretroviral drugs combined into a single pill, which helps reduce pill burden. They may combine different classes of antiretrovirals or contain only a single class. Licensed fixed-dose combinations are shown in the table below.
| Brand Name | Drug Names (INN) | Date of FDA Approval | Company |
|---|---|---|---|
| Combivir | zidovudine + lamivudine | September 26, 1997 | GlaxoSmithKline |
| Trizivir | abacavir + zidovudine + lamivudine | November 15, 2000 | GlaxoSmithKline |
| Kaletra | lopinavir + ritonavir | September 15, 2000 | Abbott Laboratories |
| Epzicom (in USA) Kivexa (in Europe) |
abacavir + lamivudine | August 2, 2004 | GlaxoSmithKline |
| Truvada | emtricitabine + tenofovir | August 8, 2006 | Gilead Sciences |
| Atripla | efavirenz + emtricitabine + tenofovir | July 12, 2006 | Gilead Sciences Bristol-Myers Squibb |
| Complera | rilpivirine + emtricitabine + tenofovir | August 10, 2011 | Gilead Sciences Johnson & Johnson |
| Stribild | elvitegravir + cobicistat + emtricitabine + tenofovir | August 27, 2012 | Gilead Sciences |
Famous quotes containing the word combination:
“I am opposed to writing about the private lives of living authors and psychoanalyzing them while they are alive. Criticism is getting all mixed up with a combination of the Junior F.B.I.- men, discards from Freud and Jung and a sort of Columnist peep- hole and missing laundry list school.... Every young English professor sees gold in them dirty sheets now. Imagine what they can do with the soiled sheets of four legal beds by the same writer and you can see why their tongues are slavering.”
—Ernest Hemingway (1899–1961)