EPH Receptor B2

EPH Receptor B2

Identifiers Symbols EPHB2; CAPB; DRT; EK5; EPHT3; ERK; Hek5; PCBC; Tyro5 External IDs OMIM: 600997 MGI: 99611 HomoloGene: 37925 ChEMBL: 3290 GeneCards: EPHB2 Gene EC number 2.7.10.1

Gene Ontology
Molecular function	• protein tyrosine kinase activity • transmembrane-ephrin receptor activity • receptor binding • ATP binding • axon guidance receptor activity
Cellular component	• integral to plasma membrane • axon • dendrite • neuronal cell body
Biological process	• angiogenesis • urogenital system development • protein phosphorylation • nervous system development • axon guidance • axonal fasciculation • learning • phosphorylation • peptidyl-tyrosine phosphorylation • optic nerve morphogenesis • central nervous system projection neuron axonogenesis • corpus callosum development • retinal ganglion cell axon guidance • inner ear morphogenesis • ephrin receptor signaling pathway • positive regulation of long-term neuronal synaptic plasticity • camera-type eye morphogenesis • negative regulation of axonogenesis • regulation of body fluid levels • positive regulation of synapse assembly • palate development • dendritic spine development • dendritic spine morphogenesis • commissural neuron axon guidance
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 2048 13844 Ensembl ENSG00000133216 ENSMUSG00000028664 UniProt P29323 A3KG01 RefSeq (mRNA) NM_004442 NM_010142 RefSeq (protein) NP_004433 NP_034272 Location (UCSC) Chr 1:
23.04 – 23.24 Mb Chr 4:
136.65 – 136.84 Mb PubMed search

Ephrin type-B receptor 2 is a protein that in humans is encoded by the EPHB2 gene.