Enzymatic Reaction - Induced Fit

Induced Fit

The favored model for the enzyme-substrate interaction is the induced fit model. This model proposes that the initial interaction between enzyme and substrate is relatively weak, but that these weak interactions rapidly induce conformational changes in the enzyme that strengthen binding.

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Famous quotes containing the words induced and/or fit:

    Few can be induced to labor exclusively for posterity; and none will do it enthusiastically. Posterity has done nothing for us; and theorize on it as we may, practically we shall do very little for it, unless we are made to think we are at the same time doing something for ourselves.
    Abraham Lincoln (1809–1865)

    This is mere madness,
    And thus a while the fit will work on him.
    Anon, as patient as the female dove
    When that her golden couplets are disclosed,
    His silence will sit drooping.
    William Shakespeare (1564–1616)