EIF4E

EIF4E

Identifiers Symbols EIF4E; CBP; EIF4E1; EIF4EL1; EIF4F External IDs OMIM: 133440 MGI: 95305 HomoloGene: 123817 ChEMBL: 4848 GeneCards: EIF4E Gene

Gene Ontology
Molecular function	• RNA cap binding • translation initiation factor activity • protein binding
Cellular component	• cytoplasmic mRNA processing body • cytosol • mRNA cap binding complex • cytoplasmic stress granule • eukaryotic translation initiation factor 4F complex • RNA-induced silencing complex
Biological process	• G1/S transition of mitotic cell cycle • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay • nuclear-transcribed mRNA poly(A) tail shortening • mRNA export from nucleus • translation • translational initiation • regulation of translation • insulin receptor signaling pathway • gene expression • RNA metabolic process • mRNA metabolic process • virus-host interaction • cytokine-mediated signaling pathway • cellular protein metabolic process • positive regulation of mitotic cell cycle
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 1977 13684 Ensembl ENSG00000151247 ENSMUSG00000028156 UniProt P06730 P63073 RefSeq (mRNA) NM_001130678 NM_007917 RefSeq (protein) NP_001124150 NP_031943 Location (UCSC) Chr 4:
99.79 – 99.85 Mb Chr 3:
138.53 – 138.56 Mb PubMed search

Eukaryotic translation initiation factor 4E, also known as eIF4E, is a protein that in humans is encoded by the eIF4E gene.