Effect of Caffeine On Memory - Long-term Memory

Long-term Memory

Caffeine has been shown to have positive, negative, and no effects on long-term memory. When studying the effects of this and any drug, potential ethical restraints on human study procedures may lead researchers to conduct studies involving animal subjects in addition to human subjects.

Researchers have found that long-term consumption of low dose caffeine slowed hippocampus-dependent learning and impaired long-term memory in mice. Caffeine consumption for 4 weeks also significantly reduced hippocampal neurogenesis compared to controls during the experiment. The conclusion was that long-term consumption of caffeine could inhibit hippocampus-dependent learning and memory partially through inhibition of hippocampal neurogenesis.

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