Side Effects and Tolerance
Side effects increase with dosage and include drowsiness, mild stomach ache, lethargy, urinary retention, bradypnea, constipation, and nausea. Nausea can be attributed to the presence of noscapine and is more common in first-time or inexperienced users. At high doses, the side effects are dangerous and can cause death through respiratory arrest or inhalation of vomit. Constipation often results from use (as with any opiate).
Additionally, frequent use results in high tolerance and dependence. Chemical dependency builds in relation to the frequency of use, dose used, age, gender, weight, and medical condition. Once chemical dependency has developed, abrupt cessation of use will cause withdrawal; symptoms include leg and abdominal cramps, mydriasis, vomiting, diarrhea, headache, insomnia, cravings, lethargy, and anxiety. As users are addicted to all the different alkaloids found in the opium poppy, withdrawal symptoms can be worse and/or more prolonged than those experienced by users of just one opioid. Symptoms of withdrawal usually fade after 4–10 days but cravings and psychological dependence may continue for longer, in some cases up to a year. Treatment methods for addiction are generally the same for any opioid.
Read more about this topic: Doda (drug)
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