Activity
DNA polymerase III synthesizes base pairs at a rate of around 1000 nucleotides per second. DNA Pol III activity begins after strand separation at the origin of replication. Because DNA synthesis cannot start de novo, an RNA primer, complementary to part of the single-stranded DNA, is synthesized by primase (an RNA polymerase):
("!" for RNA, '"$" for DNA, "*" for polymerase)
--------> * * * * ! ! ! ! _ _ _ _ _ _ _ _ | RNA | <--ribose (sugar)-phosphate backbone G U A U | Pol | <--RNA primer * * * * |_ _ _ _| <--hydrogen bonding C A T A G C A T C C <--template ssDNA (single-stranded DNA) _ _ _ _ _ _ _ _ _ _ <--deoxyribose (sugar)-phosphate backbone $ $ $ $ $ $ $ $ $ $Read more about this topic: DNA Polymerase III Holoenzyme
Famous quotes containing the word activity:
“In communist society, where nobody has one exclusive sphere of activity but each can become accomplished in any branch he wishes, society regulates the general production and thus makes it possible for me to do one thing today and another tomorrow, to hunt in the morning, fish in the afternoon, rear cattle in the evening, criticize after dinner, just as I have a mind, without ever becoming hunter, fisherman, shepherd or critic.”
—Karl Marx (1818–1883)
“The animal is one with its life activity. It does not distinguish the activity from itself. It is its activity. But man makes his life activity itself an object of his will and consciousness. He has a conscious life activity. It is not a determination with which he is completely identified.”
—Karl Marx (1818–1883)
“A worm is as good a traveler as a grasshopper or a cricket, and a much wiser settler. With all their activity these do not hop away from drought nor forward to summer. We do not avoid evil by fleeing before it, but by rising above or diving below its plane; as the worm escapes drought and frost by boring a few inches deeper.”
—Henry David Thoreau (1817–1862)