Diuretic - Adverse Effects

Adverse Effects

The main adverse effects of diuretics are hypovolemia, hypokalemia, hyperkalemia, hyponatremia, metabolic alkalosis, metabolic acidosis and hyperuricemia.

Adverse effect Diuretics Symptoms
Hypovolemia
  • loop diuretics
  • thiazides
  • lassitude
  • thirst
  • muscle cramps
  • hypotension
hypokalemia
  • acetazolamides
  • loop diuretics
  • thiazides
  • muscle weakness
  • paralysis
  • arrhythmia
Hyperkalemia
  • amilorides
  • triamterenes
  • spironolactone
  • arrhythmia
  • muscle cramps
  • paralysis
hyponatremia
  • thiazides
  • furosemides
  • CNS symptoms
    • coma
metabolic alkalosis
  • loop diuretics
  • thiazides
  • arrhythmia
  • CNS symptoms
metabolic acidosis
  • acetazolamides
  • amilorides
  • triamterene
  • Kussmaul respirations
  • muscle weakness
  • neurological symptoms
    • lethargy
    • coma
    • seizures
    • stupor
hypercalcemia
  • thiazides
  • gout
  • tissue calcification
  • fatigue
  • depression
  • confusion
  • anorexia
  • nausea
  • vomiting
  • constipation
  • pancreatitis
  • increased urination
hyperuricemia
  • thiazides
  • loop diuretics
  • gout

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