Dimitrie Cantemir Lyceum (Romanian: Liceul "Dimitrie Cantemir"; Russian: Лицей Имени Дмитрия Кантемира) of Chişinău, Moldova is a state institution of primary and secondary education. It is named after Dimitrie Cantemir, Moldavian voivod and prolific man of letters.
Previously the 3rd school of Chişinău, it was reformed into a lyceum in 1991.
The language of teaching is Russian.
The lyceum consists of a grammar school (grades 1 to 4), a junior high school (or gymnasium; grades 5 to 9), and a high school (or lyceum; grades 10 to 12).
Dimitrie Cantemir Lyceum of Chişinău is considered to be one of the best institutions of secondary education in Chişinău.