Deoxyribose-phosphate Aldolase

In enzymology, a deoxyribose-phosphate aldolase (EC 4.1.2.4) is an enzyme that catalyzes the chemical reaction

2-deoxy-D-ribose 5-phosphate D-glyceraldehyde 3-phosphate + acetaldehyde

Hence, this enzyme has one substrate, 2-deoxy-D-ribose 5-phosphate, and two products, D-glyceraldehyde 3-phosphate and acetaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming). Other names in common use include phosphodeoxyriboaldolase, deoxyriboaldolase, deoxyribose-5-phosphate aldolase, 2-deoxyribose-5-phosphate aldolase, and 2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase. This enzyme participates in pentose phosphate pathway.