Decarboxylation - in Biochemistry

In Biochemistry

Common biosynthetic oxidative decarboxylations of amino acids to amines are:

  • tryptophan to tryptamine
  • phenylalanine to phenylethylamine
  • tyrosine to tyramine
  • histidine to histamine
  • serine to ethanolamine
  • glutamic acid to GABA
  • lysine to cadaverine
  • arginine to agmatine
  • ornithine to putrescine
  • 5-HTP to serotonin
  • L-DOPA to dopamine

Other decarboxylation reactions from the citric acid cycle include:

  • pyruvate to acetyl-CoA
  • oxalosuccinate to α-ketoglutarate
  • α-ketoglutarate to succinyl-CoA.

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