Decarboxylation - Case Studies

Case Studies

Upon heating, Δ9-Tetrahydrocannabinolic acid decarboxylates to give the psychoactive compound Δ9-Tetrahydrocannabinol. In beverages stored for long periods, very small amounts of benzene may form from benzoic acid by decarboxylation catalyzed by the presence of vitamin C. The addition of catalytic amounts of cyclohexenone has been reported to catalyze the decarboxylation of amino acids. However, using such catalysts may also yield an amount of unwanted by-products.

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