Awards and Nominations
| Year | Award | Category | Work | Result |
|---|---|---|---|---|
| 2000 | American Comedy Award | Best Female Performer in a TV Series | Will & Grace | Nominated |
| Emmy Award | Outstanding Lead Actress in a Comedy Series | Nominated | ||
| Golden Globe Award | Best Actress in a TV Series – Comedy or Musical | Nominated | ||
| Viewers for Quality Television Award | Best Actress in a Comedy Series | Nominated | ||
| 2001 | American Comedy Award | Best Female Performer in a TV Series | Nominated | |
| Emmy Award | Outstanding Lead Actress in a Comedy Series | Nominated | ||
| Golden Globe Award | Best Actress in a TV Series – Comedy or Musical | Nominated | ||
| Screen Actors Guild Award | Outstanding Performance by an Ensemble in a Comedy Series | Won | ||
| Outstanding Performance by a Female Actor in a Comedy Series | Nominated | |||
| Teen Choice Award | Choice TV Actress | Nominated | ||
| TV Guide Award | Actress of the Year in a Comedy Series | Won | ||
| 2002 | Emmy Award | Outstanding Lead Actress in a Comedy Series | Nominated | |
| Golden Globe Award | Best Actress in a TV Series – Comedy or Musical | Nominated | ||
| Satellite Award | Best Actress in a TV Series – Comedy or Musical | Won | ||
| Screen Actors Guild Award | Outstanding Performance by an Ensemble in a Comedy Series | Nominated | ||
| Teen Choice Award | Choice TV Actress | Nominated | ||
| 2003 | Emmy Award | Outstanding Lead Actress in a Comedy Series | Won | |
| Golden Globe Award | Best Actress in a TV Series – Comedy or Musical | Nominated | ||
| Satellite Award | Best Actress in a TV Series – Comedy or Musical | Won | ||
| Screen Actors Guild Award | Outstanding Performance by an Ensemble in a Comedy Series | Nominated | ||
| 2004 | Golden Globe Award | Best Actress in a TV Series – Comedy or Musical | Nominated | |
| Satellite Award | Best Actress in a TV Series – Comedy or Musical | Nominated | ||
| Screen Actors Guild Award | Outstanding Performance by an Ensemble in a Comedy Series | Nominated | ||
| Outstanding Performance by a Female Actor in a Comedy Series | Nominated | |||
| 2005 | Golden Globe Award | Best Actress in a TV Series – Comedy or Musical | Nominated | |
| People’s Choice Award | Best Female TV Star | Nominated | ||
| Best Female Comedic Star | Nominated | |||
| Screen Actors Guild Award | Outstanding Performance by an Ensemble in a Comedy Series | Nominated | ||
| 2006 | Emmy Award | Outstanding Lead Actress in a Comedy Series | Nominated | |
| Teen Choice Award | Choice TV Actress | Nominated | ||
| 2007 | Emmy Award | Outstanding Lead Actress in a Mini Series or TV Movie | The Starter Wife | Nominated |
| Satellite Award | Best Actress in a Mini Series or TV Movie | Nominated | ||
| 2008 | Golden Globe Award | Best Actress in a Mini Series or TV Movie | Nominated | |
| Gracie Allen Award | Outstanding Female Lead in a Mini Series | Won | ||
| Screen Actors Guild Award | Outstanding Female Actor in a Mini Series or TV Movie | Nominated | ||
| 2009 | Golden Globe Award | Best Actress in a TV Series – Comedy or Musical | Nominated | |
| Satellite Award | Best Actress in a Motion Picture – Comedy or Musical | Nothing Like the Holidays | Nominated | |
| 2012 | Pan-American Association of Film & Television Journalists Award | Best Cast in a Drama Series | Smash | Nominated |
| Women's Image Network Award | Best Actress in a Drama Series | Pending |
Read more about this topic: Debra Messing