Dean Hamer - Human Behavior Genetics

Human Behavior Genetics

In the 1990s Hamer began studies of the role of genes in human behavior. In 1993 he published a paper suggesting the existence of genes that influence homosexuality in males, and presented evidence that one of these genes is associated with the Xq28 marker on the X chromosome. This finding was replicated in two studies in the United States but not in a third in Canada; meta-analysis indicated Xq28 has a significant but not exclusive effect. Subsequently, several additional linked regions on other chromosomes have been described.

In 1996, Hamer and colleagues investigated the genetic roots of anxiety and found that the gene for the serotonin transporter, which is the target of antidepressant drugs such as Prozac, is partially responsible. This polymorphism has been extensively replicated and its activity has been confirmed by direct brain imaging studies. More recently, Hamer has postulated the existence of a God gene for religious experience. This work, which was featured on the cover of Time magazine, has been controversial.

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