CYP2C8

CYP2C8

Identifiers Symbols CYP2C8; CPC8; CYPIIC8; MP-12/MP-20 External IDs OMIM: 601129 MGI: 1917138 HomoloGene: 117948 ChEMBL: 3721 GeneCards: CYP2C8 Gene EC number 1.14.14.1

Gene Ontology
Molecular function	• monooxygenase activity • iron ion binding • electron carrier activity • heme binding • caffeine oxidase activity • aromatase activity
Cellular component	• endoplasmic reticulum • endoplasmic reticulum membrane
Biological process	• organic acid metabolic process • xenobiotic metabolic process • drug metabolic process • exogenous drug catabolic process • small molecule metabolic process • oxidation-reduction process • oxidative demethylation
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 1558 13095 Ensembl ENSG00000138115 ENSMUSG00000003053 UniProt P10632 Q64458 RefSeq (mRNA) NM_000770.3 NM_007815.3 RefSeq (protein) NP_000761.3 NP_031841.3 Location (UCSC) Chr 10:
96.8 – 96.83 Mb Chr 19:
39.27 – 39.33 Mb PubMed search

Cytochrome P₄₅₀2C8 (abbreviated CYP2C8), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body.