CYP2B6

CYP2B6

Identifiers Symbols CYP2B6; CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450 External IDs OMIM: 123930 MGI: 88598 HomoloGene: 73894 ChEMBL: 4729 GeneCards: CYP2B6 Gene EC number 1.14.14.1

Gene Ontology
Molecular function monooxygenase activity
iron ion binding
electron carrier activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
heme binding
Cellular component endoplasmic reticulum
endoplasmic reticulum membrane
intracellular membrane-bounded organelle
Biological process xenobiotic metabolic process
steroid metabolic process
drug metabolic process
cellular ketone metabolic process
exogenous drug catabolic process
small molecule metabolic process
oxidation-reduction process
Sources: Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1555 13088 Ensembl ENSG00000197408 ENSMUSG00000030483 UniProt P20813 Q6LCL8 RefSeq (mRNA) NM_000767.4 NM_009999.3 RefSeq (protein) NP_000758.1 NP_034129.1 Location (UCSC) Chr 19:
41.5 – 41.52 Mb Chr 7:
25.9 – 25.93 Mb PubMed search

Cytochrome P450 2B6 is an enzyme that in humans is encoded by the CYP2B6 gene. CYP2B6 is a member of the Cytochrome P450 group of enzymes. Along with CYP2A6, it is involved with metabolizing nicotine, along with many other substances.

Read more about CYP2B6:  Function, Gene, CYP2B6 Ligands