Cyclobenzaprine - Interactions

Interactions

Cyclobenzaprine has major contraindications with monoamine oxidase inhibitors (MAOIs). At least one study also found increased risk of serotonin syndrome when cyclobenzaprine was taken with the serotonergic drugs duloxetine or phenelzine.

The following substances may interact with cyclobenzaprine:

  • Alcohol
  • Central nervous system (CNS) depressants (medicines that cause drowsiness)
  • Tricyclic antidepressants may increase the chance of side effects.
  • Monoamine oxidase inhibitors taken within two weeks of cyclobenzaprine may result in serious, life-threatening side effects.

Read more about this topic:  Cyclobenzaprine

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