Structure
A CNG channel consists of four subunits around a central pore. Each protein subunit consists 6 transmembrane segments (S1-S6), a P-loop, intracellular amino terminal region, and carboxy terminal region. The P-loop and S6 segments around the pore, which plays a role in ion conduction. There is a cyclic nucleotide binding domain (CNBD) and connection region to the S6 segment in the carboxy terminal. There is a post-CNDB region in the amino terminal.
Read more about this topic: Cyclic Nucleotide-gated Ion Channel
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