Central Dogma
The difference in selector gene activity not only establishes two compartments, but also leads to the formation of a boundary between these two that serves as a source of morphogen gradients. In the central dogma of compartments, first, morphogen gradients position founder compartment cells. Then, active/inactive selector genes give a unique genetic identity to cells within a compartment, instructing their fate and their interactions with the neighboring compartment. Finally, border cells, established by short-range signaling from one compartment to its neighboring compartment emit long-range signals that spread to both compartments to regulate the growth and pattering of the entire tissue.
Read more about this topic: Compartment (development)
Famous quotes containing the words central and/or dogma:
“The Federal Constitution has stood the test of more than a hundred years in supplying the powers that have been needed to make the Central Government as strong as it ought to be, and with this movement toward uniform legislation and agreements between the States I do not see why the Constitution may not serve our people always.”
—William Howard Taft (1857–1930)
“We call a man a bigot or a slave of dogma because he is a thinker who has thought thoroughly and to a definite end.”
—Gilbert Keith Chesterton (1874–1936)