Central Dogma
The difference in selector gene activity not only establishes two compartments, but also leads to the formation of a boundary between these two that serves as a source of morphogen gradients. In the central dogma of compartments, first, morphogen gradients position founder compartment cells. Then, active/inactive selector genes give a unique genetic identity to cells within a compartment, instructing their fate and their interactions with the neighboring compartment. Finally, border cells, established by short-range signaling from one compartment to its neighboring compartment emit long-range signals that spread to both compartments to regulate the growth and pattering of the entire tissue.
Read more about this topic: Compartment (development)
Famous quotes containing the words central and/or dogma:
“Et in Arcadia ego.
[I too am in Arcadia.]”
—Anonymous, Anonymous.
Tomb inscription, appearing in classical paintings by Guercino and Poussin, among others. The words probably mean that even the most ideal earthly lives are mortal. Arcadia, a mountainous region in the central Peloponnese, Greece, was the rustic abode of Pan, depicted in literature and art as a land of innocence and ease, and was the title of Sir Philip Sidney’s pastoral romance (1590)
“From the age of fifteen, dogma has been the fundamental principle of my religion: I know no other religion; I cannot enter into the idea of any other sort of religion; religion, as a mere sentiment, is to me a dream and a mockery.”
—Cardinal John Henry Newman (1801–1890)