Presentation
Coats’ usually affects only one eye (unilateral) and occurs predominantly in young males, with the onset of symptoms generally appearing in the first decade of life. Peak age of onset is between 6-8 years of age, but onset can range from 5 months to 71 years.
Coats’ disease results in a gradual loss of vision. Blood leaks from the abnormal vessels into the back of the eye, leaving behind cholesterol deposits and damaging the retina. Coats’ normally progresses slowly. At advanced stages, retinal detachment is likely to occur. Glaucoma, atrophy, and cataracts can also develop secondary to Coats’ disease. In some cases, removal of the eye may be necessary (enucleation).
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