Co-receptor Localization and Function
Depending on the type of ligand a co-receptor binds, its location and function can vary. Various ligands include interleukins, neurotrophic factors, fibroblast growth factors, transforming growth factors, vascular endothelial growth factors and epidermal growth factors. Co-receptors prominent in embryonic tissue have an essential role in morphogen gradient formation or tissue differentiation. Co-receptors localized in endothelial cells function to enhance cell proliferation and cell migration. With such variety in regards to location, co-receptors can participate in many different cellular activities. Co-receptors have been identified as participants in cell signalling cascades, embryonic development, cell adhesion regulation, gradient formation, tissue proliferation and migration.
Read more about this topic: Co-receptor
Famous quotes containing the word function:
“The mother’s and father’s attitudes toward the child correspond to the child’s own needs.... Mother has the function of making him secure in life, father has the function of teaching him, guiding him to cope with those problems with which the particular society the child has been born into confronts him.”
—Erich Fromm (1900–1980)