CHRNB2
Gene Ontology | |
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Molecular function | • acetylcholine-activated cation-selective channel activity • ligand-gated ion channel activity • acetylcholine receptor activity • acetylcholine binding |
Cellular component | • plasma membrane • acetylcholine-gated channel complex • external side of plasma membrane • integral to membrane • cell junction • postsynaptic membrane |
Biological process | • conditioned taste aversion • response to hypoxia • ion transport • calcium ion transport • smooth muscle contraction • signal transduction • synaptic transmission • synaptic transmission, cholinergic • visual perception • sensory perception of sound • learning • memory • locomotory behavior • associative learning • visual learning • regulation of dopamine secretion • sensory perception of pain • vestibulocochlear nerve development • optic nerve morphogenesis • lateral geniculate nucleus development • central nervous system projection neuron axonogenesis • positive regulation of B cell proliferation • regulation of synaptic transmission, dopaminergic • positive regulation of synaptic transmission, dopaminergic • positive regulation of dopamine secretion • response to nicotine • behavioral response to nicotine • social behavior • regulation of dopamine metabolic process • B cell activation • response to cocaine • regulation of circadian sleep/wake cycle, REM sleep • regulation of circadian sleep/wake cycle, non-REM sleep • response to ethanol • negative regulation of action potential • regulation of dendrite morphogenesis • neurological system process • cognition • membrane depolarization • regulation of synapse assembly • synaptic transmission involved in micturition |
Sources: Amigo / QuickGO |
154.54 – 154.55 Mb
89.75 – 89.76 Mb
Neuronal acetylcholine receptor subunit beta-2 is a protein that in humans is encoded by the CHRNB2 gene.
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.
Read more about CHRNB2: Interactive Pathway Map