Entertainment
- Chattahoochee (film), a 1989 film starring Gary Oldman and Dennis Hopper set at the Florida State Hospital
- "Chattahoochee" (song), a 1993 song by Alan Jackson named for the Chattahoochee River
- "Chattahoochee", a song by 38 Special on their album Rock & Roll Strategy, named for the Florida State Hospital
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