Cerebral Atrophy - Associated Diseases and Disorders

Associated Diseases and Disorders

The pattern and rate of progression of cerebral atrophy depends on the disease involved. Diseases that cause cerebral atrophy include:


  • stroke and traumatic brain injury
  • Major depressive disorder
  • Alzheimer's disease, Pick’s disease, senile dementia, fronto-temporal dementia, and vascular dementia
  • cerebral palsy, in which lesions (damaged areas) may impair motor coordination
  • Huntington's disease, and other genetic disorders that cause build-up of toxic levels of proteins in neurons
  • leukodystrophies, such as Krabbe disease, which destroy the myelin sheath that protects axons
  • mitochondrial encephalomyopathies, such as Kearns-Sayre syndrome, which interfere with the basic functions of neurons
  • multiple sclerosis, which causes inflammation, myelin damage, and lesions in cerebral tissue
  • infectious diseases, such as encephalitis, neurosyphilis, and AIDS, in which an infectious agent or the inflammatory reaction to it destroys neurons and their axons
  • epilepsy, in which lesions cause abnormal electrochemical discharges that result in seizures
  • Anorexia Nervosa, Bulimia Nervosa, and other Eating Disorders
  • Malnutrition

Read more about this topic:  Cerebral Atrophy

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