CD44
Gene Ontology | |
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Molecular function | • hyalurononglucosaminidase activity • transmembrane signaling receptor activity • protein binding • collagen binding • hyaluronic acid binding |
Cellular component | • plasma membrane • integral to plasma membrane • external side of plasma membrane • cell surface • basolateral plasma membrane |
Biological process | • branching involved in ureteric bud morphogenesis • wound healing involved in inflammatory response • carbohydrate metabolic process • cell-matrix adhesion • positive regulation of gene expression • Wnt receptor signaling pathway • cell-cell adhesion • cytokine-mediated signaling pathway • glycosaminoglycan metabolic process • hyaluronan metabolic process • hyaluronan catabolic process • positive regulation of peptidyl-serine phosphorylation • positive regulation of heterotypic cell-cell adhesion • negative regulation of apoptotic process • negative regulation of cysteine-type endopeptidase activity involved in apoptotic process • negative regulation of DNA damage response, signal transduction by p53 class mediator • small molecule metabolic process • cellular response to fibroblast growth factor stimulus • positive regulation of peptidyl-tyrosine phosphorylation • cartilage development • interferon-gamma-mediated signaling pathway • branching involved in prostate gland morphogenesis • positive regulation of ERK1 and ERK2 cascade • monocyte aggregation • positive regulation of monocyte aggregation |
Sources: Amigo / QuickGO |
35.16 – 35.25 Mb
102.81 – 102.9 Mb
The CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. In humans, the CD44 antigen is encoded by the CD44 gene on Chromosome 11.
Read more about CD44: Tissue Distribution and Isoforms, Function, Clinical Significance, Interactions