Bioactivity Studies
Catechin is reported to induce longevity in the nematode worm Caenorhabditis elegans. Transcriptomic studies shows that catechin reduces atherosclerotic lesion development in apo E-deficient mice. (+)- and (−)-catechin seem to have stereospecific opposite effects on glycogen metabolism in isolated rat hepatocytes. (+)-Catechin inhibits intestinal tumor formation in mice. (+)-Catechin inhibits the oxidation of low density lipoprotein.
(-)-Catechin suppresses expression of Kruppel-like factor 7.
Catechin shows an enhancement of the antifungal effect of amphotericin B against Candida albicans.
Incubation experiments with (+)-catechin show a prevention of human plasma oxidation.
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