Carbonic Anhydrase VI

Identifiers Symbols CA6; CA-VI; GUSTIN External IDs OMIM: 114780 MGI: 1333786 HomoloGene: 20324 ChEMBL: 3025 GeneCards: CA6 Gene EC number 4.2.1.1

Gene Ontology
Molecular function	• carbonate dehydratase activity • zinc ion binding • metal ion binding
Cellular component	• extracellular region • extracellular space • cytoplasm
Biological process	• one-carbon metabolic process • bicarbonate transport • small molecule metabolic process
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 765 12353 Ensembl ENSG00000131686 ENSMUSG00000028972 UniProt P23280 P18761 RefSeq (mRNA) NM_001215 NM_009802 RefSeq (protein) NP_001206 NP_033932 Location (UCSC) Chr 1:
9.01 – 9.04 Mb Chr 4:
150.19 – 150.2 Mb PubMed search

Carbonic anhydrase 6 (also called 'Gustin') is an enzyme that in humans is encoded by the CA6 gene.

The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide, though its function in saliva is unknown.