BCR Gene
| Gene Ontology | |
|---|---|
| Molecular function | • protein serine/threonine kinase activity • protein tyrosine kinase activity • Rho guanyl-nucleotide exchange factor activity • GTPase activator activity • protein binding • ATP binding • phospholipid binding • kinase activity • Rac GTPase activator activity |
| Cellular component | • cytosol • plasma membrane |
| Biological process | • protein phosphorylation • signal transduction • small GTPase mediated signal transduction • brain development • actin cytoskeleton organization • negative regulation of cell migration • response to lipopolysaccharide • inner ear morphogenesis • negative regulation of neutrophil degranulation • negative regulation of inflammatory response • positive regulation of phagocytosis • neuromuscular process controlling balance • regulation of small GTPase mediated signal transduction • regulation of cell cycle |
| Sources: Amigo / QuickGO | |
23.52 – 23.66 Mb
75.06 – 75.18 Mb
| Bcr-Abl oncoprotein oligomerisation domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| structure of the bcr-abl oncoprotein oligomerization domain | |||||||||
| Identifiers | |||||||||
| Symbol | Bcr-Abl_Oligo | ||||||||
| Pfam | PF09036 | ||||||||
| InterPro | IPR015123 | ||||||||
The breakpoint cluster region protein (BCR) also known as renal carcinoma antigen NY-REN-26 is a protein that in humans is encoded by the BCR gene. BCR is one of the two genes in the BCR-ABL complex, which is associated with the Philadelphia chromosome. Two transcript variants encoding different isoforms have been found for this gene. Read more about BCR Gene: Function, Clinical Significance, Structure, Interactions | |||||||||