Ashikaga Yoshikane (足利義兼?, 1154? - April 5, 1199) was a Japanese samurai military commander, feudal lord in the late Heian and early Kamakura period of Japan's history. He played an active part in the Jishō-Juei War and the later military campaign as a closely related person of the first Kamakura shogun Minamoto no Yoritomo, and made Ashikaga clan influential position in gokenin vassal of the Kamakura Shogunate.