Apolipoprotein C1

Apolipoprotein C1

Identifiers Symbol APOC1 External IDs OMIM: 107710 MGI: 88053 HomoloGene: 1244 GeneCards: APOC1 Gene

Gene Ontology
Molecular function phospholipase inhibitor activity
fatty acid binding
phosphatidylcholine binding
lipase inhibitor activity
phosphatidylcholine-sterol O-acyltransferase activator activity
Cellular component endoplasmic reticulum
very-low-density lipoprotein particle
high-density lipoprotein particle
chylomicron
Biological process lipid metabolic process
positive regulation of cholesterol esterification
negative regulation of phosphatidylcholine catabolic process
negative regulation of very-low-density lipoprotein particle clearance
regulation of cholesterol transport
negative regulation of cholesterol transport
cholesterol efflux
phospholipid efflux
plasma lipoprotein particle remodeling
high-density lipoprotein particle remodeling
very-low-density lipoprotein particle assembly
chylomicron remnant clearance
very-low-density lipoprotein particle clearance
lipoprotein metabolic process
negative regulation of fatty acid biosynthetic process
negative regulation of lipid metabolic process
negative regulation of receptor-mediated endocytosis
negative regulation of lipid catabolic process
negative regulation of lipoprotein lipase activity
Sources: Amigo / QuickGO
Orthologs Species Human Mouse Entrez 341 11812 Ensembl ENSG00000130208 ENSMUSG00000040564 UniProt P02654 P34928 RefSeq (mRNA) NM_001645.3 NM_001110009.1 RefSeq (protein) NP_001636.1 NP_001103479.1 Location (UCSC) Chr 19:
45.42 – 45.42 Mb Chr 7:
19.69 – 19.69 Mb PubMed search
ApoC-I
structural studies of a baboon (papio sp.) plasma protein inhibitor of cholesteryl ester transferase.
Identifiers
Symbol ApoC-I
Pfam PF04691
InterPro IPR006781
SCOP 1ale
SUPERFAMILY 1ale
Available protein structures:
Pfam structures
PDB RCSB PDB; PDBe
PDBsum structure summary

Apolipoprotein C-I is a protein component of lipoproteins that in humans is encoded by the APOC1 gene.

Read more about Apolipoprotein C1:  Function, Interactive Pathway Map