APOA4

APOA4

Identifiers Symbols APOA4; MGC142154; MGC142156 External IDs OMIM: 107690 MGI: 88051 HomoloGene: 47927 GeneCards: APOA4 Gene

Gene Ontology
Molecular function	• lipid transporter activity • copper ion binding • lipid binding • antioxidant activity • cholesterol transporter activity • phosphatidylcholine binding • protein homodimerization activity • eukaryotic cell surface binding • phosphatidylcholine-sterol O-acyltransferase activator activity
Cellular component	• extracellular region • extracellular space • endoplasmic reticulum lumen • cell surface • very-low-density lipoprotein particle • high-density lipoprotein particle • chylomicron
Biological process	• innate immune response in mucosa • lipid metabolic process • lipid transport • response to lipid hydroperoxide • leukocyte cell-cell adhesion • cholesterol metabolic process • positive regulation of cholesterol esterification • positive regulation of triglyceride catabolic process • removal of superoxide radicals • regulation of intestinal cholesterol absorption • regulation of cholesterol transport • cholesterol efflux • phospholipid efflux • chylomicron remodeling • very-low-density lipoprotein particle remodeling • high-density lipoprotein particle remodeling • chylomicron assembly • negative regulation of plasma lipoprotein particle oxidation • response to stilbenoid • lipoprotein metabolic process • cholesterol homeostasis • hydrogen peroxide catabolic process • reverse cholesterol transport • multicellular organismal lipid catabolic process • small molecule metabolic process • positive regulation of fatty acid biosynthetic process • phosphatidylcholine metabolic process • positive regulation of lipoprotein lipase activity • lipid homeostasis • protein-lipid complex assembly
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 337 11808 Ensembl ENSG00000110244 ENSMUSG00000032080 UniProt P06727 P06728 RefSeq (mRNA) NM_000482 NM_007468 RefSeq (protein) NP_000473 NP_031494 Location (UCSC) Chr 11:
116.69 – 116.69 Mb Chr 9:
46.24 – 46.24 Mb PubMed search

Apolipoprotein A-IV (also known as apoA-IV, apoAIV, or apoA4) is plasma protein that is the product of the human gene APOA4.