Andronikos Palaiologos or Andronicus Palaeologus may refer to:
- Andronikos Palaiologos (megas domestikos), father of Michael VIII Palaiologos
- Andronikos Palaiologos (protostrator) (died between 1281 and 1286), nephew or cousin of Michael VIII Palaiologos
- Andronikos II Palaiologos (1259–1332), Byzantine emperor from 1282 to 1328
- Andronikos Palaiologos (archon) (fl. 1326/8), Byzantine lord of Berat under Andronikos II
- Andronikos III Palaiologos (1297–1341), Byzantine emperor from 1321 to 1341, sole emperor from 1328
- Andronikos IV Palaiologos (1348–1385), Byzantine emperor from 1376 to 1379
- Andronikos V Palaiologos (c. 1400–1407), son of John VII Palaiologos, co-emperor from c. 1403 to his death
- Andronikos Palaiologos (1404–1428), son of Manuel II Palaiologos, governor of Thessalonica from 1408 to 1423