Examples and Structure
Four structural classes of ampakine drugs have been developed so far:
- the pyrrolidine derivative racetam drugs such as piracetam and aniracetam
- the CX- series of drugs which encompass a range of benzoylpiperidine and benzoylpyrrolidine structures
- benzothiazide derivatives such as cyclothiazide and IDRA-21
- biarylpropylsulfonamides such as LY-392,098, LY-404,187, LY-451,646 and LY-503,430
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“No rules exist, and examples are simply life-savers answering the appeals of rules making vain attempts to exist.”
—André Breton (1896–1966)
“Agnosticism is a perfectly respectable and tenable philosophical position; it is not dogmatic and makes no pronouncements about the ultimate truths of the universe. It remains open to evidence and persuasion; lacking faith, it nevertheless does not deride faith. Atheism, on the other hand, is as unyielding and dogmatic about religious belief as true believers are about heathens. It tries to use reason to demolish a structure that is not built upon reason.”
—Sydney J. Harris (1917–1986)