Amie may refer to:
- Amie, an alternate spelling of the female personal name Amy
- AMIE, the Associate Member of the Institution of Engineers, a professional certification given by India's Institution of Engineers
- "Amie", the 1972 song from the album Bustin' Out by Pure Prairie League
- "Amie", a song by artist Damien Rice
- Amie, daughter of Massasoit and wife to Tispaquin
- Amie Fern, a party member character from the video game Neverwinter Nights 2