Allotopic expression (AE) refers to expression from the nuclear genome of genes that normally are expressed only from the mitochondrial genome. Biomedically engineered AE has been suggested as a possible future tool in gene therapy of certain mitochondria-related diseases (de Grey 2000), however this view is controversial (Oca-Cossio et al. 2003).
Famous quotes containing the word expression:
“An unlicked bear”
—Trans. by Johanna Prins.
Dutch expression meaning “a boor”: from the old belief that bear cubs are licked into shape by their mothers.