Early Development
In 1943 plant biologist Arthur Galston began studying the compound triiodobenzoic acid as a plant growth hormone, in an attempt to adapt soybeans to a short growing season. Galston found that excessive usage of the compound caused catastrophic defoliation — a finding later used by his colleague Ian Sussex to develop the family of herbicides used in Operation Ranch Hand. Galston was especially concerned about the compound's side effects to humans and the environment.
In 1943, the U.S. Department of the Army contracted the University of Chicago to study the effects of 2,4-D and 2,4,5-T on cereal grains (including rice) and broadleaf crops. From these studies arose the concept of using aerial applications of herbicides to destroy enemy crops to disrupt their food supply. In early 1945, the U.S. army ran tests of various 2,4-D and 2,4,5-T mixtures at the Bushnell Army Airfield in Florida, which is now listed as a Formerly Used Defense Site (FUDS).
Read more about this topic: Agent Orange
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