Disease Association
Compared to non-O group (A, AB, and B) individuals, O group individuals have a 14% reduced risk of squamous cell carcinoma and 4% reduced risk of basal cell carcinoma. It is also associated with a reduced risk of pancreatic cancer. The B antigen links with increased risk of ovarian cancer. Gastric cancer has reported to be more common in blood group A and least in group O.
According to Glass, Holmgren, et al., those in the O blood group have an increased risk of infection with cholera, and those O-group individuals who are infected have more severe infections. The mechanisms behind this association with cholera are currently unclear in the literature. The title of the referenced article is: "Predisposition for cholera of individuals with O blood group. Possible evolutionary significance."
Read more about this topic: ABO Blood Group System
Famous quotes containing the words disease and/or association:
“Your responsibility as a parent is not as great as you might imagine. You need not supply the world with the next conqueror of disease or a major movie star. If your child simply grows up to be someone who does not use the word collectible as a noun, you can consider yourself an unqualified success.”
—Fran Lebowitz (20th century)
“An association of men who will not quarrel with one another is a thing which has never yet existed, from the greatest confederacy of nations down to a town meeting or a vestry.”
—Thomas Jefferson (17431826)