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- Edith Abbott (1876–1957), American social worker, educator, and author
- Edville Gerhardt Abbott (1871–1938), American orthopædic surgeon
- Edward Abbott, several people, including:
- Edward Abbott (clergyman) (1841–1908), American clergyman, journalist, and author
- Edward Abbott (jurist) (1766–1832), Australian soldier and politician
- Edwin Abbott (1808–1882), English educator
- Edwin Abbott Abbott (1838–1926), British schoolmaster and theologian
- Edwin Milton Abbott (1877–1940), American lawyer and poet
- Elenore Abbott (1875–1935), American book illustrator, scenic designer, and artist
- Eleanor Hallowell Abbott (1872–1958), American author
- Emma Abbott (1849–1891), American singer
- Eric Symes Abbott (1906–1983), English clergyman
- Evelyn Abbott (1843–1901), English classical scholar
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