The 1998 National League Division Series (NLDS), the opening round of the 1998 National League playoffs, began on Tuesday, September 29, and ended on Sunday, October 4, with the champions of the three NL divisions—along with a "wild card" team—participating in two best-of-five series. The teams were:
- (1) Atlanta Braves (Eastern Division champion, 106–56) vs. (4) Chicago Cubs (Wild Card, 90–73): Braves win series, 3–0.
- (2) Houston Astros (Central Division champion, 102–60) vs. (3) San Diego Padres (Western Division champion, 98–64): Padres win series, 3–1.
The higher seed (in parentheses) had the home field advantage, which for the first time was determined by playing record. Also for the first time, the team with home field advantage played the first two games at home, with potentially Game 5 at home as well; previously, the team with the home field "advantage" had played the first two games on the road, with the possibility of the final three games at home. The Cubs had won the wild card spot through a one-game playoff with the San Francisco Giants, winning 5–3 on September 28.
The Atlanta Braves and San Diego Padres went on to meet in the NL Championship Series (NLCS). The Padres defeated the Braves four games to two to become the National League champion, and lost to the American League champion New York Yankees in the 1998 World Series.
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