100 North Main Street

100 North Main Street, also known as Wells Fargo Center, is a postmodern, 460-foot (140 m), 34-floor office skyscraper in Winston-Salem, North Carolina, USA. Originally named Wachovia Center, the building served as the corporate headquarters of Wachovia bank from 1995, the year of the tower's construction, to 2001, the year the corporation merged with First Union and moved its headquarters to Charlotte, North Carolina. It is the tallest building in the Piedmont Triad region and was the tallest in the Carolinas outside of Charlotte until 2008, when the RBC Plaza (Now PNC Plaza) was completed in Raleigh.

The building was designed by Petronas Towers architect César Pelli and features Moravian architectural themes, which are widely found in Winston-Salem. Notable aspects include the Moravian arch, which was used in the dome's design, and the Moravian star, which was used on the lobby's mosaics. Pelli said the tower design resembled a rosebud about to bloom. It is sheathed in Olympia white granite and is the only granite-domed skyscraper in the world. The granite comes from a single quarry in Sardinia. The dome rises 59 feet and houses mechanical equipment. The gardens around the site were designed by Cesar Pelli's wife Diana Balmori, a landscape architect.