Zira may refer to:
- Zira, a lioness and the antagonist in Disney's 1998 direct-to-video animated film The Lion King II: Simba's Pride
- Zira (Planet of the Apes), a chimpanzee character in the novel and movie series Planet of the Apes
- Zira, TellMe voice persona
- ZirÉ™, Azerbaijan
- Zira, India, a small town in Ferozepur, Punjab, India
- Zira, Iran, a village in Bushehr Province, Iran
- Zira (Cumin), a flowering plant native from east Mediterranean to East India
- "Zira (Call Out My Name)", Redd Kross song