Zinc Finger Nuclease
Zinc-finger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNA-binding domain to a DNA-cleavage domain. Zinc finger domains can be engineered to target desired DNA sequences and this enables zinc-finger nucleases to target unique sequences within complex genomes. By taking advantage of endogenous DNA repair machinery, these reagents can be used to precisely alter the genomes of higher organisms.
Read more about Zinc Finger Nuclease: DNA-cleavage Domain, DNA-binding Domain, Applications, Prospects, Zinc-finger Nickases
Famous quotes containing the word finger:
“There in the narrow,
mote-filled finger of light, is a blonde
so blonde, so blinding, she is a blizzard, a huge
spook, and lights up like the sun the audience
in its galoshes. She bulges like a deuce coupe.
When we see her we say good-bye to Kansas.”
—Lynn Emanuel (b. 1949)