Zhu or ZHU may refer to:
- Zhu (surname), common Chinese surnames
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- Zhu Yuanzhang, first emperor of the Ming Dynasty
- Zhu River, or Pearl River, in southern China
- Zhu (state), ancient Chinese state, later renamed Zou.
- Zhu (string instrument), ancient Chinese string instrument
- Zhu (percussion instrument), ancient Chinese percussion instrument
- Zhuhai Sanzao Airport - ZHU is the 3 letter IATA code for the airport
- Zhu languages
- Houston Air Route Traffic Control Center, known as ZHU