Zelos may refer to:
- An alternate spelling of Zelus of Greek mythology
- Zelos Wilder, a character in the Nintendo GameCube game Tales of Symphonia
- The Silver Gigas in the videogame Skies of Arcadia
- Zelos, the main antagonist from Konami's side-shooter; Salamander (video game)'
- Frog Zelos, a character in Saint Seiya