Z6 small nucleolar RNA is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. Z6 snoRNA belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Famous quotes containing the word small:
“We must remain as close to the flowers, the grass, and the butterflies as the child is who is not yet so much taller than they are. We adults, on the other hand, have outgrown them and have to lower ourselves to stoop down to them. It seems to me that the grass hates us when we confess our love for it.—Whoever would partake of all good things must understand how to be small at times.”
—Friedrich Nietzsche (1844–1900)