Z18 small nucleolar RNA (also known as SNORD74 and U74) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. Z18 snoRNA belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.
Famous quotes containing the word small:
“All adults who care about a baby will naturally be in competition for that baby.... Each adult wishes that he or she could do each job a bit more skillfully for the infant or small child than the other.”
—T. Berry Brazelton (20th century)