Yarborough may refer to:
- Charles Anderson-Pelham, 2nd Earl of Yarborough, after whom the bridge hand is named
- A yarborough is an especially weak hand in contract bridge
- Earl of Yarborough, a hereditary title in the Peerage of the United Kingdom
- Cale Yarborough, retired NASCAR driver and three time Winston Cup Champion
- Emmanuel Yarborough, an American Sumo wrestler
- Ralph Yarborough, a Texas politician (1903 - 1996)
- William P. Yarborough, a Brigadier General during the Kennedy administration