Safety
Xylenes are not highly toxic as indicated by the high values of the LD50, which range from 200 to 4000 mg/kg for animals. The principal mechanism of detoxification is oxidation to methylbenzoic acid and hydroxylation to hydroxylene. However, the material safety data sheet (MSDS) rating assigned is for a moderate hazard, indicating safe handling precautions should include goggles, protective clothing, ventilation, and proper gloves, with storage of the material in a cool, dry, well-ventilated location since it is highly flammable.
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