WZ may refer to:
- WZ sex-determination system, also known as the ZW sex-determination system
- Swaziland FIPS 10-4 country code
- an abbreviation for the German city Wetzlar
- an abbreviation for the American band White Zombie
- WinZip, a computer file compression software
- an abbreviation for the Korean online gaming developer Wizet; also a file extension created by them (.wZ)
- WZ theory, a technique for simplifying certain combinatorial summations in mathematics