Wyer may refer to:
- Doug Wyer, an English speedway rider
- John Wyer (1909-1989), an automobile racing engineer and team manager
- Reginald Wyer (1898-1970), British cinematographer
- Russell Wyer, an Australian rugby league player
- WYER (FM), a radio station (90.5 FM) licensed to serve Carmi, Illinois, United States
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